Scientist DMPK at AstraZeneca i Göteborg

Publicerad: 2017-06-13
Göteborg, Västra Götalands län
Life Science
Läkemedel, bioteknik & medicinteknik
Sista ansökningsdag:
Eleonor Ehrman
Are you interested in being a part of a global pharmaceutical company with focus on bioanalytical chemistry? Do you have experience of LC-MS/MS and passion in working with bioanalytical drug discovery and development? Then you might fit the role.


The Arena:
AstraZeneca lead their industry in their development of a strong and varied pipeline. This means their people are there to win. AstraZeneca give you a breadth of opportunities to be curious and do cutting edge, unique work that has big impact on science and medicine.


Cardiovascular & Metabolic Diseases (CVMD) is one of the three main therapeutic research area within Innovative Medicines and Early Development (IMED) which deliver candidate drugs into late-stage clinical development. CVMD is based in AstraZeneca’s world-class vibrant R&D center, located in Gothenburg, Sweden. CVMD DMPK interacts with other functions in supporting CVMD projects all along the value chain, from target selection all the way to market launch and Life cycle management.


AstraZeneca is now looking for a bioanalytical scientist with in depth knowledge in the area of quantitative bioanalysis of drugs and drug metabolites to join their team in the CVMD DMPK department for a consultant assignment. The team you will be part of is focusing on metabolism, bio-distribution and disposition of small molecule, conjugated peptide and nucleotide drug candidates. You will have the opportunity to contribute to the discovery of new life changing medicines for patients and demonstrate and witness what science can do.


Tasks and responsibilities:
You will be responsible for analysing drug candidates and their metabolites in various in vitro and in vivo samples including sub-cellular fractions as well as tissues, plasma and bile samples.

Your responsibility will include delivering quality in vitro and in vivo bioanalytical data including analysis of drugs, drug candidates and drug metabolites in various in vitro and in vivo samples including cells, sub-cellular fractions, tissues, plasma, and bile samples to support PKPD (Pharmacokinetics and Pharmacodynamics) and biotransformation work in projects from target selection to LCM (life cycle management). The data generated is mainly aimed to provide insight to quantitative pharmacology as well as to right tissue and right exposure aspects including the fates of drug molecules/metabolites.

This laboratory based scientific role includes developing and validating methods to enable delivery of data with the necessary quality and scientific information aligned with the project needs. The role requires interactive, effective communication to provide clear data and guidance to project representatives, act as an example to other scientists, and contribute to the overall team delivery. It will also require making judgements about bioanalysis information, developing innovative solutions and applying cross-disciplinary understanding.


Minimum requirements and key factors:

  • M.Sc or equivalent degree in a relevant discipline
  • Track record of delivering state-of-the-art bioanalysis data to projects in discovery and/or development setting
  • Good knowledge of liquid chromatography and mass spectrometry ionization and detection (LC-MS/MS) and bioanalytical work in Drug Discovery & Development
  • Basic understanding of DMPK
  • Understanding of the overall drug discovery and development process
  • Good communication skills in English, both verbal and in writing are required
  • Demonstrated ability to work in team and independently
Business: Dfind Science & Engineering

City: Göteborg

Deadline for applications: 2017-06-20. Please send in your application as soon as possible as we interview ongoing!

More information:
For further information contact Eleonor Ehrman +46733434109 or Stefan Bäckström

Organization/Business description:
Dfind Science & Engineering is part of Randstad, one of the Nordic regions’ largest specialists within staffing, recruitment and outplacement. Dfind Science & Engineering is specialized in recruitment and consulting providing competences within Life Science, Science and Engineering and is a company where people make all the difference. At Dfind Science & Engineering specialists are recruiting specialists! All our recruitment consultants, consultants and sourcing managers have a technical or scientific background, combined with extensive networks within relevant communities and expertise within recruitment and HR. We understand our customers specific requirements and know how to find the best candidates. Through our passionate commitment and high degree of attentiveness we help people and businesses to grow and be competitive in a changing world.