Computational Chemist at AstraZeneca R&D Gothenburg.

Publicerad:
2019-05-16
Omfattning:
Heltid
Kontakt:
Kerstin Karlsson

Detaljer

Publicerad:
2019-05-16
Ort:
Göteborg, Västra Götalands län
Kategori:
Life Science
Specialisering:
Läkemedel, bioteknik & medicinteknik
Omfattning:
Heltid
Referensnummer:
201224213
Sista ansökningsdag:
2019-05-23
Kontakt:
Kerstin Karlsson

Beskrivning

Do you have expertise in Computational and Medicinal Chemistry? Would you like to join a world leading team that push the boundaries of science to deliver life-changing medicines? Then you might be the one we are looking for!

We are looking for a Computational Chemist that can join AstraZeneca's Computational Chemistry team for a consultant position for approximately 1.5 year, 2020-03-01.

AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

The Computational Chemistry team use of state of the art in silico methods for modelling, ligand and structure-based design, data analysis, property predictions and data analysis supporting the Cardiovascular, Renal and Metabolic (CVRM) drug discovery projects. The team operates in a highly cross disciplinary environment in close collaboration with scientists from the Chemistry, Bioscience, DMPK and Pharmaceutical Sciences departments to advance the CVRM project pipeline.

This is a compchem project support (drug hunting) position, where you are expected to impact multiple projects across the CVRM portfolio with a focus on target identification, lead generation and lead optimization including “New Modalities” such as Peptides and Macrocycles. Previous experience and if you can start immediately is an advantage.

Main Duties and Responsibilities

  • Impact simultaneously multiple discovery projects by efficiently and pro-actively applying a wide variety of computer-aided drug design approaches.
  • The work will include helping project teams analyze, interpret and visualize biological data and the communication of results within project teams and departments.

Essential requirements
We are seeking a drug hunter with a PhD (or equivalent experience) in computational chemistry, biophysics, or a related field with industry experience who would like to join our fast-pace multidisciplinary CVRM computational chemistry team. The candidate is expected to have a high degree of independence and a proven record of excellence in a number of computer-aided drug design techniques to assist in target identification and advancement of discovery programs.

  • Solid knowledge of computational chemistry and medicinal chemistry concepts
  • Expertise in using and improving computational chemistry software as well as knowledge in scientific computing, and programming skills (e.g. Python, Perl, C, C++, Java)
  • Expertise in using chemoinformatics techniques
  • Experience of non-target based strategies (e.g. phenotypic screens) and or experience of computational chemistry applied on peptides, macrocycles or nucleotides will be seen as an advantage
  • Very good written and verbal communication skills

It is important for us to make use of all skills in the labor market. We welcome all applicants and strive for diversity.

About Dfind Science & Engineering
Dfind Science & Engineering is a consulting and recruitment company offering a meaningful career as a consultant in engineering and science. With us, you have the opportunity to develop your skills and build your resume through various assignments at our development, research and production-intensive customers while receiving support and guidance from your consultant manager. We are authorized through the Competence Agencies of Sweden and comply with their collective union agreement. We also have benefits such as healthcare, occupational health insurance, insurance and discount on gym memberships.

Dfind Science & Engineering is part of Randstad, a global leader in the HR services industry. First of June, Dfind Science & Engineering changes name to Randstad. We will retain our organization and, above all, our strong specialization towards science and engineering within what will become Randstad Life Sciences and Randstad Engineering.

Deadline for application: 2019-05-23, selection and interviews will take place continuously. The position may be filled before the closing date, so please apply as soon as possible.

For more information contact: Kerstin Karlsson kerstin.karlsson@dfind.se or Eleonor Ehrman 073-343 41 09.

Please keep in mind, e-mail applications will not be considered. Register your profile at Dfind Science & Engineering's webpage and send in your application there.